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Funding Information This work is made possible through benefactor support of the Inhaled Particle Aerosol Laboratory (IPAL) and Community Internal Medicine at Mayo Clinic Rochester, MN

Exposure to carcinogens Smoking tobacco produces more than 70 carcinogens such as polycyclic aromatic hydrocarbons (PAHs) and cadmium

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Direct surface irritation and tear-film disruption from smoke or vapor are usually the more immediate cause, but nicotine adds a secondary effect through the bloodstream

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