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Cotinine is produced when the body breaks down the nicotine found in tobacco smoke and second hand smoke can be detected by measuring its levels in saliva, blood or urine

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Quantification showed that consistent with the data on vascular leakage area and CNV volume, Plerixafor significantly reduced both PDGFR and -SMA positive areas, as well as the number of CD8 + T cells, effectively counteracting the effects of smoke exposure (Supplementary Fig