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But even with these limitations, the take-home message is clear, the researchers concluded

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The objective in creating a joint is to evenly distribute the cannabis within the paper, ensuring its rolled tightly for an even burn

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We have also revealed for the first time the full neural effects of active (simulated) smoking, which includes activation in a network of cortical (motor, insula, cingulate, amygdala) and sub-cortical (putamen, thalamus) regions, with relative deactivation in ventral striatum and orbitofrontal cortex