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Our preliminary interpretation is that replacement of Tyr110 indeed affects the interaction with GSH but, as compared to K105A/Y, does not drastically alter the ratio between the steady-state concentrations of the deprotonated and glutathionylated enzyme species E and F, respectively
A simple liver enzyme panel screen can alert a practitioner to the need for a deeper dive into diagnostic procedures such as an ultrasound, which is used to confirm the NAFLD diagnosis
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