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PMID 28153641

Die Hard 2 was a major box-office success, grossing $240 million and doubling the earnings of its predecessor and finishing as the year's seventh-highest-grossing film

The United States, in particular, has a sizable share, thanks to customer demand for novel vape goods, widespread product availability, and legislative developments that shape the market

These detrimental effects are mediated by complex mechanisms, including direct hepatotoxicity, oxidative stress, immune dysregulation, oncogenic signaling, and systemic metabolic disturbances