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This kind of study wont happen anytime soon, however, because weed is technically still illegal in the U.S

Smoking Cessation Counseling: Understanding a patients pack years can help healthcare providers emphasize the importance of quitting smoking and tailor cessation strategies to the individuals needs

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In addition, although the design is pragmatic to include those with psychiatric or substance use comorbidities, trial burden (weekly visits, adherence to the protocol) might make retention problematic for these participants