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RSL3 increased oxidized membrane lipid levels, as measured by confocal and flow cytometry using the dye C11-BODIPY in CRC DTP cells compared to the parental cells, supporting the notion of increased susceptibility of CRC persister cells to ferroptosis after 5-FU or AZ628 treatment ( Figures 3G, H )

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Lang F, Jilani K, Lang E

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Methods Experimental animals The study was conducted using male TPH1 knockout mice and wild-type C57BL/6 mice (46 weeks, 2126 g) (Animal Feeding Center of Xi'an Jiaotong University Health Science Center)