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Our results show that CS exposure using the CFAX12 induced a ~ 60% reduction in trans-barrier electrical resistance (TER), increased ROS generation depending on cellular model complexity, and a ~ 4.5-fold increase in IL-8 gene expression, all key hallmarks of early COPD pathogenesis
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Smoking and Tobacco Use (2022)
doi:10.1080/00913367.1994.10673447
Funding This work was supported by the Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan (18590815 and 21590898) and a Grant in Aid of Japanese Arteriosclerosis Prevention Fund
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