Product Attributes CAS # : 252977-78-1 Molecular Formula : C37H56N10O11 Sequence (AA) : KQAGSSS Molecular Weight : 824.9 g/mol Half-Life : ~7 days (extended CNS activity) Synonyms : PE 22-28, Spadin analog, Truncated spadin peptide Type : Synthetic research peptide (TREK-1 channel blocker) Research Focus : Cognitive & Neurological, Mood & Stress Modulation Scientific References Spadin, a sortilin-derived peptide, targeting rapid-acting antidepressant Animal | In vitro Antidepressant-like effects of PE-22-28, a TREK-1 channel blocker Animal Identification of a novel antidepressant peptide based on the structure of spadin Animal | In vitro TREK-1 channel as a new target for fast-acting antidepressants Animal | In vitro Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype Animal Spadin as a new antidepressant: absence of TREK-1-related side effects Animal Two-pore domain potassium channels as therapeutic targets in mood disorders Observational | Animal | In vitro Included In The Box Every product arrives in a premium, custom-designed PEPTIDE.Power box , engineered for convenience, hygiene, and safe storage in your refrigerator
It's important to be honest here: pharmaceutical GLP-1 drugs (Ozempic, Wegovy, Mounjaro) are powerful, clinically validated medications for obesity and type 2 diabetes
Deficiencies are rare but can cause brittle hair and nails
Evidentiary breathalysers convert breath alcohol concentration (BrAC) to a BAC-equivalent using a standard 2100:1 partition ratio food does not change this conversion
Related: GHK-Cu Peptide Complete Guide: Benefits, Dosage, & Everything You Need to Know Last updated: December 2025
The body isn't fragmented but the payment system is, and the people who carry both diagnoses pay the highest cost of that fragmentation
