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Compared with placebo, the likelihood of quitting smoking was roughly doubled with NRT (1.84, 95% CI 1.711.99) and bupropion (1.82, 1.602.06) and was improved further with varenicline (2.88, 2.403.47) (Cahill et al., 2013)

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M., Tanabe, K

Men are slightly more affected by smoking, with a higher percentage of men smoking compared to women