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According to research by the National Institute on Drug Abuse, published in 2022, stimulant users experience a 50% increase in dopamine activity, which contributes to both the therapeutic effects and addictive potential of these drugs

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It was observed that smokers have an elevated level of circulating markers of inflammation like C-reactive protein and interleukin-6 [7, 75], and also increased levels of VCAM-1 and ICAM-1, which indicates higher adhesion of immune cells to the endothelium [51]

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