Semaglutide treatment commenced at 0.25 mg per week for the initial 4 weeks using a pre-filled pen injector, with a fixed-dose escalation every 4 weeks until reaching the maintenance dose of 2.4 mg by week 16 (lower maintenance doses allowed if 2.4 mg was intolerable for participants)
Patients who pair it with meaningful lifestyle changes, such as healthier eating habits and regular exercise, achieve better and more sustainable results
Higher concentrations (like 30 mg/mL) require very precise small-volume draws
An FDA decision is anticipated by late 2026
Unlike allodynia, which specifically involves pain from non-painful stimuli, dysesthesia encompasses a broader range of abnormal sensations including tingling, prickling, crawling, and numbness
Opened Pen Protocol: Once in use, you can keep the pen at room temperature (below 30C) or in the fridge for up to 30 days