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This is an important distinction: reduced exposure and reduced harms are not the same thing, meaning exposure to fewer toxic ingredients, especially in the context of dual use of both e-cigarettes and combustible products, does not necessarily mean lower levels of harm when people use the product

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But the United States and Canada had among the highest rates of dependence on marijuana (749 cases per 100,000 people), opioids (650 cases per 100,000) and cocaine (301 cases per 100,000), according to study co-author Robert West, of University College London, and colleagues

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