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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: April 5, 2026 Smoking significantly worsens acid reflux and GERD by weakening the lower esophageal sphincter (LES), increasing stomach acid production, and impairing the esophaguss ability to clear acid

In the univariate analysis, several factors were found to be significantly associated with SLT consumption: being aged 46 years (OR=7.10