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Discover the complexities of nicotine delivery, from traditional cigarettes to e-cigarettes, and the implications for public health

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The accumulation of ROS can trigger oxidative stress, damaging cellular components, while NO promotes stress tolerance and signaling pathways (Goraya et al., 2017).Heat stress results in the overproduction of cytosolic Ca 2+ , ROS, and NO, disrupting the endoplasmic reticulums protein-folding capacity (ER)