Transporters of secondary metabolites
This creates a buildup of toxic metabolic byproducts, like lactic acid, which further irritates the already damaged nerve endings, exacerbating both the neuropathic pain and the profound post-exertional malaise (PEM) that defines these conditions
Were left wondering, How are GLP-1s causing these effects? asks senior author Marc Montminy, MD, PhD, a biochemist, physiologist, and distinguished professor emeritus at Salk
GI side effects occurred in up to 50%, mostly mild to moderate
If you have diabetes and take insulin or a sulfonylurea, ask about low blood sugar as a possible contributor
Cormio L, Zizzi V, Bettocchi C et al: Tunica albuginea plication for the correction of penile curvature