Menstrual changes result from reversible metabolic and hormonal shifts rather than ovarian failure
In addition to combining pharmacotherapy with lifestyle or surgical interventions, there is potential benefit of combining different pharmacotherapies to target multiple pathways or organs
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doi: 10.1038/s41598-024-51832-y 144
The expression and distribution of FFARs such as GPR40, GPR119, and GPR120 in L and cells and glucose, along with their dual effects on insulin and GLP-1 secretion, have made them attractive therapeutic targets, leading to the development of agonists for these receptors for the treatment of T2DM [150,151,152,153,154]
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