Chewing tobacco contains several cancer-causing agents including acetaldehyde, formaldehyde, benzopyrene, arsenic, cadmium, and nickel
Brendryen H, Kraft P
Probably they are organic acids that have surfaced as a result of pH or other changes in the chemistry of the leaf as it ages
Smoking is a risk factor for high blood pressure, which can lead to heart attack and stroke
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In the photo, I look youthful for a 65-year-old, and Paul looks positively spectacular for a 95-year-old