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It is seen most often in middle-aged or older adults and occurs most frequently on the tongue, floor of mouth, and soft palate

But there is some research, such as that by Filbey, Gohel, Prashad, and Biswal [4] , that suggests that the concomitant use of cannabis and tobacco together does result in unique brain states

There is evidence that other influences, such as alcohol, caffeine, other psychoactive drugs, hormones, diet, sleep, and stress also affect brain development

The best way to prevent the risks of cannabis use is to avoid it

Rohinipriyanka Pondugula MBBS Last updated on 6th Mar, 2026 Introduction Smoking is one of the leading causes of preventable diseases and death worldwide

The increases in e-cigarette use over the past two years have been driven by the 18- to 24-year-old age group and 65.5% of e-cigarette users in this age group did not smoke cigarettes previously in 2022, the report says