Consequently, it is crucial to assess the risks and benefits for each elderly patient individually and to implement appropriate monitoring and interventions
Chiu TTY, Rogers MS, Briton-Jones C, Haines C
Our study had certain limitations
The pain may feel like mild to moderate pressure, aching, or throbbing, and it can affect the forehead, temples, back of the head, or one side
In the first sensitivity analysis comparing the risk of incident NAION in persons with T2D treated with SGLT2 inhibitors alone ( n = 40,206, reference), once-weekly semaglutide alone ( n = 71,658), and once-weekly semaglutide and SGLT2 inhibitors combined ( n = 45,401), we observed 6 events in 82,877 person-years, 36 events in 178,868 person-years, and 31 events in 119,106 person-years, respectively, corresponding to adjusted HR of 242 (95% CI 097 606) and 262 (95% CI 102674) for once-weekly semaglutide without and with SGLT2 inhibitors in a multivariable model adjusted for sex, age, marital status, duration of diabetes, hemoglobin A1c, estimated glomerular filtration rate, cardiovascular disease, use of insulin, use of cholesterol-lowering medicine, and use of blood pressure lowering medicine
These may include job interviews, public speaking or airplane flights
