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Along with the script/director changes, I suppose the cast changes were involved as well

In lung cells, they found that on average, smoking a pack of cigarettes a day led to 150 mutations in each cell every year

Rodent longitudinal models suggest that after eight months of exposure to e-cigarettes containing nicotine, significant differences in arterial stiffness were observed, similar to mice exposed to combustible tobacco product smoke [84]

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Looking ahead Overall, the results of this study illustrate that, just like smoking, vaping has the potential to make already dangerous bacteria more harmful