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GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of antioxidant genes

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Nuclear mitochondrial gene abnormalities were ruled-out using an oligonucleotide array with comparative genomic hybridization analysis that examines 180 nuclear genes involved in mitochondria function, including genes involved in fatty-acid oxidation, carnitine metabolism, mitochondrial biogenesis, mtDNA maintenance, transcription and translation, and ETC complex assembly (MitoMet, Baylor Medical Genetics Laboratory)

Melasma can sometimes lighten if triggers are removed, but it often returns, especially with sun or heat exposure

They're called glucagon-like peptide-1 (GLP-1) receptor agonists

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