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This is because the FDA regulates the testing and approval of drugs, but not how doctors use drugs to treat their patients

References: Kecel-Gunduza S, Kocb E, Bicaka B, Kokcub Y, Ozela AE, Akyuzc S

A practitioner asking should I offer MIC? in 2026 is implicitly asking why would I, when I can prescribe a GLP-1? The honest answers are narrower than the marketing, but they are real: Patients who cannot or will not take a GLP-1

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Structures that were not wild-type, lacked protein-ligand complexes with covalent ligands, or had a resolution higher than 3.2 were excluded

Scientists for the agency spoke extensively about the lack of reliable data for any of the seven peptides before the committee