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Certain conditions may blunt or impede therapeutic response to cyanocobalamin therapy

10.1016/j.yrtph.2020.104665 24 XueX

Schoenenberger 1984

BPC-157 has the most extensive preclinical literature for vascular applications: studies published in journals including Vascular Pharmacology and Journal of Physiology and Pharmacology demonstrate accelerated healing of severed blood vessels, improved blood flow in ischemic tissue, and reduced thrombosis formation

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While vitamin B12 is generally considered safe, excessive intake, especially through supplementation, may lead to side effects in some individuals