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Acknowledgements The authors thank Gregory Conner PhD for his insightful guidance and expertise, Professor Marianne Geiser for her valuable comments in preparing the manuscript, Nathalie Baumlin for her technical assistance with HBE cell cultures and Mir Anwar for his assistance with the fluorescence immunohistochemistry micrographs

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In the majority of cases, the virus only causes a mild illness that typically includes typical flu-like symptoms like headache, fever, nausea, vomiting, muscle aches and joint aches

Cigarette smoking among adults United States, 2004