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The balance of chemical products contained in the leaves defines tobacco quality: in order to be considered a valuable product, the leaves have to contain carbohydrates, pigments, resins, essential oils and natural elements

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However , its availability is influenced by location and supply issues

This opportunistic pathogen possesses a sophisticated arsenal of virulence factors permitting a suite of infections ranging in severity from superficial skin infections to life-threatening pneumonia or endocarditis 24