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There is some evidence to suggest that an increase in receptor expression may be involved in the development of cough hypersensitivity, as evidenced by an increase in TRPV1 expression in the lungs of chronic coughers compared to healthy controls (Groneberg et al., 2004)

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doi:10.18332/tid/156836 11

The Layla Sessions liner notes, page 12

As more research points to sugars role in reinforcing nicotines effects and increasing toxic byproducts in smoke, the need for greater public awareness becomes more urgent