the coase theorem claims that in the case of tobacco Economics Clean Air Ch.10: Coase Theorem, Pro

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The reduced levels of harmful chemicals has not been linked to reduced risk to health (in fact, the United States Food and Drug Administration specifically noted that PMI has not demonstrated that IQOS will significantly reduce harm or the risk of tobacco-related diseases)

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More research on the long-term impacts of ENDS use on the cardiovascular system are needed, but short-term studies show harm

This is a problem, as another study suggested that clozapine may be less effective if treatment is delayed beyond three years.(3)(4) 5