Existing research has primarily focused on mucosal changes related to prior snus use, reporting improvements in lesion prevalence or severity, yet these findings are based on small samples, limited follow-up periods and self-reported outcomes, which restrict the strength of evidence ( Nevertheless, toxicological assessments indicate that switching completely from smoking to nicotine pouches may substantially reduce exposure to established carcinogens (59)
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A Stress level changes Quitting smoking causes cravings for nicotine, which This can worsen constipation because the hormones released during stress can slow intestinal movement and increase inflammation
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According to the World Health Organization, oral epithelial dysplasia is associated with an increased risk of progression to squamous cell carcinoma [45]
