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Further investigation is necessary to understand the relationship between the Nrf2 signaling pathway and autophagy as well as their role(s) in the corneal epithelial cellular defense against CSE-induced injury

Additionally, studies on marginal bone loss indicate greater bone loss in smokers (2.5 mm) than in non-smokers (1.1 mm)

100 12.5.6.5 Advantages and disadvantages of biomarkers There are many advantages to using biomarkers to estimate human exposure to tobacco smoke

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But while a 2021 review concluded that warnings increased the perceived harms of smoking and users intentions to quit, they gradually become less effective over time as people acclimate to the new design