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In vivo studies require optimization based on model and objectives
The study demonstrated that MOTS-c levels in the blood of centenarians, individuals who have survived to 100 years and older, were significantly higher than in age-matched individuals with shorter lifespans, and resembled levels seen in much younger adults [2]
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The findings revealed that BPC-157 accelerated the outgrowth of tendon fibroblasts, enhanced the survival of these cells under H2O2-induced stress, and promoted the migration and spreading of tendon fibroblasts in a dose-dependent manner
Shi F, Zhang Z, Cui H, Wang J, Wang Y, Tang Y, et al