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However, from the available peptides that reached the level of clinical trials, the presented results are limited

N Engl J Med 370(15):13831392 Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ et al (2003) Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial

Topiramate Compared to GLP-1 Agents and Phentermine Topiramate targets the psychological and behavioral aspects of eating more strongly than GLP-1 agents or phentermine

These data confirmed that exogenous NMN treatment elevated ovarian NMN, replenishing its levels following its depletion by Dox treatment (Fig

There is also other early research that shows that GLP-1 can be an effective treatment for drug or alcohol addiction, so we will likely see the medication be used beyond diabetes and obesity in the future.

The ACHIEVE program for type 2 diabetes includes ACHIEVE-1 (NCT05971940, completed), ACHIEVE-2 (NCT06192108, completed), ACHIEVE-3 (NCT06045221, completed), ACHIEVE-4 (NCT05803421), ACHIEVE-5 (NCT06109311, completed), and ACHIEVE-J (NCT06010004, Japan-specific)