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PLoS One (2011) 6(9):e24097.10.1371/journal.pone.0024097 57 EltomSBelvisiMGStevensonCSMaherSADubuisEFitzgeraldKAet alRole of the inflammasome-caspase1/11-IL-1/18 axis in cigarette smoke driven airway inflammation: an insight into the pathogenesis of COPD