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When nicotine intake stops, withdrawal symptoms include cravings for nicotine, anger/irritability, anxiety, depression, impatience, trouble sleeping, restlessness, hunger or weight gain, and difficulty concentrating

Defendants argued that the menthol was added to the cigarette filters, and not the tobacco, so the additive-free natural tobacco label was truthful, but when the cigarette is smoked, inevitably the menthol intermingles with the tobacco, making the claim inherently misleading

Freebase nicotine was popularized in the 1960s when researchers discovered that by treating tobacco with ammonia, they could convert more of its natural nicotine into freebase form

If chemical irritants or allergens are causing nosebleeds, it may be necessary to avoid or reduce exposure to them, take antihistamines, or wear protective masks

"There's no safe amount of secondhand smoke," the surgeon general has said

Zhang H et al