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[30] Other important components of the stomach are the interstitial cells of Cajal (ICC), which act as a pacemaker since they transduce signals from motor neurons to produce an electrical rhythm in the smooth muscle cells

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The Canadian Intense Regimen (CIR) includes 2-second puff duration, 55 milliliter (mL) puff volume, and 30-second interval (Minister of Justice, 2019), while the ISO/FTC regimen includes 2-second puff duration, 35 mL puff volume, and 60-second interval (ISO, 2012)