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Absent the unlikely situation that the additives would eliminate tobacco smoke's genotoxicity and mutagenicity, the failure to find increased toxicity associated with the additives does not support the conclusion that in vitro mutagenicity and cytotoxicity of the cigarette smoke were not increased by the addition of the ingredients [17]

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At several points in the evening Wenner is, as one fellow guest put it, visibly struggling to hold it together"

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Any inhalation into the lungs can lead to airway changes, Agrawal explains