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Klupinski and colleagues (2016) used two-dimensional gas chromatography-time of flight mass spectrometry to compare little cigar mainstream smoke with cigarette mainstream smoke

3 By the 1990s, filters had been so effectively marketed as harm-reduction tools that non-filtered cigarettes held only a negligible market-share

Of course, the above statement does not mean there were no issues

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"Many people gain weight when they quit smoking because they trade cigarettes for unhealthy food to get these feel-good chemicals back

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