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instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction

Our exposure design (two puffs with a 4-h gap and then a 24-h recovery before lysing for proteomics) was based on previously published ALI studies in our lab using a VitroCell system (Nair et al., 2020

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However, the most common method of cannabis consumption (74% of users [33]) is inhalation of the smoke produced from combustion of the dried cannabis flower from a joint or water pipe [34]