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High levels of oxygen may increase free radical generation, which is potentially detrimental to patients with brain injury

Disruption of endoplasmic reticulum function can lead to the accumulation of misfolded proteins, endoplasmic reticulum stress, and activation of the unfolded protein response (UPR)

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Retrieved from: Thompson, Edward T

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Buczkowski K, Marcinowicz L, Czachowski S, Piszczek E