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Finally the presence of numerous gold dots confirms the excellence of the work, in fact damasking a single point of small surface is technically more complicated than damasking large or long patterns

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PLoS One (2016) 11(3):e0149946.10.1371/journal.pone.0149946 61 ItoTTsujiMMoriYKandaHHidakaTKakamuTet alEffect of cyp2a6*4 genetic polymorphisms on smoking behaviors and nicotine dependence in a general population of Japanese men

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Sleep disturbances : Nicotine can reduce deep sleep and make it harder to fall asleep, particularly if used later in the day