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Open-system e-cigarettes have a clearomizer which is filled with e-liquid manually, whereas closed-system e-cigarettes use ready-filled tanks or pods of e-liquid that screw directly onto the e-cig battery

One population group which may be susceptible to such messaging is pregnant women 9,10,11 , with some studies suggesting such marketing has led to an increase in use of e-cigarettes among pregnant women 12

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Rfx2 is broadly required for ciliogenesis during vertebrate development