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The use of e-cigs has already been studied in a previous American longitudinal study, the PATH study [13], where, among 2,932 e-cig users at the baseline survey, 18% at the follow-up survey reported positive results (having stopped smoking and/or using e-cigs), versus 38% who reported negative results (having relapsed smoking), while a 44% had not recorded significant changes, since they continued to use the products they used in the baseline investigation

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Using liquid chromatographytandem mass spectrometry, Kim and Shin (2013) detected TSNAs in 105 refill liquid brands purchased from 11 e-cigarette companies in the Korean market

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