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The transcription factor FOXO 3 alpha (FOXO3a) may induce the expression of several antioxidant genes, including Mn superoxide dismutase (MnSOD), catalase, peroxiredoxins 3 and 5 (Prx3 and Prx5, respectively), thioredoxin 2 (Trx2), thioredoxin reductase 2 (TR2), and uncoupling protein 2 (UCP-2) [139]

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In our further quantitative and qualitative consideration of the packs (and the English on them), we were able to establish that English was commonly included on packs in all six countries, with China being the only country with only a minority (40%) of packs having English present on the branding space available on the front panel