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A: Patients typically notice initial benefits in sleep quality and recovery within the first few weeks

Nature 425 , 917925 (2003)

10.1016/j.neuint.2017.01.004 43 HambrightW

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PARP1 also has the ability to ADP-ribosylate and deactivate GAPDH, which results in a reduction of GAPDH levels and may, in certain situations, lead to cell death (Maher and Hanneken, 2008)

All in all, the hyperinflammation that may accompany SARS-CoV-2 infection is not only associated with severe lung pathology [115, 116], a poorer clinical outcome [115, 117] and higher mortality [118] but also with increased OSTOX/ANTIOX and somatic and mental symptoms some months later