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Endocrine effects Several studies have suggested that there are significant differences in biological response to nicotine and progression to nicotine dependence between males and females, where females are more sensitive to the effects of nicotine than males probably due to hormonal differences (Sieminska and Jassem, 2014, Chellian et al., 2020, Lee et al., 2021)
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A ten-minute test drive six years ago was all I needed to cross the porky Zed off my personal list permanently, and not even the rather stunning-looking Nismo run-out model was sufficient incentive to change my position on the matter
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