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Smoking covariates like current smoking status, years spent smoking packs, and exposure to secondhand smoke were included, along with sociodemographic factors

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Laryngeal cancer More common in men Strongly linked to tobacco and alcohol use Early diagnosis improves outcomes Radiotherapy, surgery and chemotherapy are the main treatments If the cancer is advanced, the patient may have to have surgery to remove part or all of the larynx These patients will no longer be able to speak or breathe in the usual way They will breathe through a permanent hole in their neck (stoma) and will need additional treatment to help restore their voice This may include a throat implant or an electrical device you hold against your throat to produce sound Source: NHS Choices, external One of the study authors, Prof Willie Hamilton, was the clinical lead for the current guidelines from The National Institute for Health and Care Excellence (NICE)

Early CTCL often lacks the histologic criteria necessary for a definitive diagnosis

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