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Vascular Damage and Reduced Blood Flow Nitric Oxide (NO) Suppression : Smoking reduces the bodys ability to produce NO, which is essential for blood vessel dilation during arousal

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7.3 Combination of Pharmacotherapy According to WHO, there was high-certainty evidence for combination nicotine replacement therapy (CNRT) (a patch plus a short-acting form such as gum or lozenge) in long-term quit rates than NRT alone ( 104 )

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