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Later entrants had to adopt other tactics to succeed: later entrants may be forced either to differentiate their products, thereby becoming the first entrant in a new submarket, or to "reach" a segment of potential customers which has not been tapped by the first entrant

There are still some Amish, especially in Pennsylvania and Maryland, that raise tobacco, so the product is seen as sustenance and therefore smoking is more accepted

Even after completing rehab, individuals may still experience intense cravings due to these alterations, particularly during the initial phases of recovery

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Moreover, the loss of productivity due to illness and premature deaths further compounds the economic impact