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In contrast, the subgroup difference in AOR based on study design (cohort, case-control) gave p=0.01, signifying a significant difference between these groups

Both smokers and former smokers die sooner than do never smokers, so deaths also contribute to boosting the proportion of never-smokers in the country

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Diseases caused by smoking can take 30-50 years to develop and e-cigarettes have only been in widespread use since the early 2000s

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Various studies have speculated that differences in patterns of use compared to tobacco could account for the difference, as well as the anti-inflammatory properties of certain cannabinoids