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Instead, public health officials should promote safer alternatives to combustible cigarettes, such as e-cigarettes, which have proven effective in helping smokers quit.

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What has been lacking until now among individuals with and without psychiatric disorders is a large, randomised controlled trial that directly compares these medications with placebo and an active comparator, and that systematically probes for neuropsychiatric adverse events while smokers are trying to quit. The researchers assessed the relative neuropsychiatric safety and efficacy of varenicline and bupropion compared with nicotine patches and placebo among 8,144 smokers with or without psychiatric illnesses

The situation is quite similar in Cambodias Sihanoukville Special Economic Zone in the southwestern part of the country, numerous tobacco factories owned by Chinese businesspeople have established themselves

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